A small mineral with a big job: 200 mcg of highly absorbable selenium to support your thyroid, immune system, antioxidant defenses and MOOD · MIND · MEMORY.

Selenium is an essential trace mineral, which means your body can't make it and needs a steady supply from your diet. It is the key ingredient in about 25 selenoproteins, specialized proteins that help activate thyroid hormone, power your body's antioxidant defenses and support a healthy immune response. Yet selenium levels in food depend heavily on the soil it was grown in, and soils vary widely. Brain Basics Ultra-Pure Selenomethionine delivers 200 mcg of selenium per capsule as L-selenomethionine, one of the most bioavailable forms of selenium.

Why you'll love Ultra-Pure Selenomethionine

• Supports healthy thyroid function, including the conversion of T4 into T3, the active form of thyroid hormone
• Supports your body's antioxidant defenses as a building block of glutathione peroxidase
• Supports a healthy immune response
• Supports brain health, one of the organs that holds on to selenium most tightly
• Supports healthy heart, liver, eye and connective tissue function
• Highly bioavailable: L-selenomethionine, the natural form of selenium found in foods
• One capsule a day, 90 capsules per bottle

Selenium and your thyroid: the brain connection

Your thyroid sets the pace for your energy, metabolism, mood and focus, and your brain depends on healthy thyroid hormone every day. The thyroid gland contains more selenium per gram than any other organ in the body. That's because the enzymes that convert inactive T4 into active T3 are selenoproteins. Without enough selenium, that conversion slows down. Selenium also helps protect the thyroid from the oxidative stress created as it makes hormones. For complete thyroid support, pair Ultra-Pure Selenomethionine with our Ultra Iodine Complex.

Selenium and cognition: protecting the thinking brain

Your brain is one of the body's most selenium-protected organs. When selenium is scarce, the body prioritizes delivering it to the brain, a sign of just how important it is for brain function. Here's why:

• Antioxidant defense for brain cells: The brain uses about 20% of the body's oxygen, which makes it especially vulnerable to oxidative stress. Selenium is the core of glutathione peroxidase (GPX), one of the brain's most important antioxidant enzymes, which neutralizes free radicals before they can damage delicate brain cells.
• Selenoprotein P, the brain's selenium supply line: This transport protein delivers selenium into the brain. Research shows it is essential for normal brain function, motor coordination and cognition.
• Supports a balanced inflammatory response in the brain and throughout the body.
• Supports healthy thyroid hormone activity, which drives the energy, focus and mental clarity your brain depends on every day.

What the research shows

A 2022 systematic review and meta-analysis of clinical trials, published in the journal Nutrients, pooled the results of selenium supplementation studies focused on cognitive health. Researchers found that selenium supplementation significantly increased both the body's selenium levels and the activity of glutathione peroxidase, the brain's key selenium-dependent antioxidant enzyme. Selenium supplementation was also associated with improvements on several tests of cognitive function, and the authors concluded that selenium is a valuable nutrient for supporting antioxidant status and called for further research on its cognitive benefits.

Why selenomethionine?

Selenium comes in several forms. Inorganic forms such as sodium selenite are inexpensive but less efficiently absorbed and retained. L-selenomethionine is the organic form of selenium that occurs naturally in foods such as Brazil nuts, grains and seafood. It is well absorbed and can be stored in the body, providing a steady reserve your cells can draw on.

What's inside (per capsule)

• Selenium (as L-selenomethionine), 200 mcg: 363% of the Daily Value, in its most natural, well-absorbed form

Other ingredients: vegetable capsule, silicified microcrystalline cellulose, vegetable magnesium stearate.

How to use

Take 1 capsule daily, or as directed by your healthcare practitioner. Each bottle contains 90 capsules, a three-month supply.

Quality you can trust

Ultra-Pure Selenomethionine is made in the USA in a GMP-certified, FDA-registered facility and is lab-tested for purity and potency.

Frequently asked questions

What does selenium do in the body?
Selenium is built into about 25 selenoproteins that help activate thyroid hormone, recycle antioxidants, support immune cells and protect cells from oxidative stress.

Why take selenium with iodine?
Iodine is the raw material for thyroid hormone, and selenium helps activate it and protect the thyroid while it works. The two are natural partners, which is why Ultra-Pure Selenomethionine pairs perfectly with Ultra Iodine Complex.

Can't I just get selenium from food?
Selenium content in food varies dramatically depending on where it was grown. A supplement provides a consistent, measured amount every day.

Can I take it with other Brain Bean products?
Yes. Ultra-Pure Selenomethionine is designed to work alongside our other Brain Bean products, especially Ultra Iodine Complex, Opti Zinc Plus™ and Ultra-Pure NAC for antioxidant support.

Scientific references

1. Pereira ME, Souza JV, Galiciolli MEA, et al. Effects of Selenium Supplementation in Patients with Mild Cognitive Impairment or Alzheimer’s Disease: A Systematic Review and Meta-Analysis. Nutrients. 2022;14(15):3205. doi.org/10.3390/nu14153205
2. Ventura M, Melo M, Carrilho F. Selenium and Thyroid Disease: From Pathophysiology to Treatment. International Journal of Endocrinology. 2017;2017:1-9. doi.org/10.1155/2017/1297658
3. Raichle ME, Gusnard DA. Appraising the brain's energy budget. Proceedings of the National Academy of Sciences. 2002;99(16):10237-10239. doi.org/10.1073/pnas.172399499

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.