Highly absorbable choline that reaches your brain, to support memory, focus and your MOOD · MIND · MEMORY.

Your brain uses choline to make acetylcholine, the neurotransmitter behind memory, learning, focus and the connection between your mind and muscles. Most people don't get enough choline from their diet, and many common forms of choline struggle to reach the brain. Alpha-GPC (L-alpha glycerylphosphorylcholine) is different: it is one of the most bioavailable forms of choline and readily crosses the blood-brain barrier, delivering choline right where your brain needs it. Every capsule of Brain Basics Ultra Alpha-GPC provides 250 mg of pure Alpha-GPC.

Why you'll love Ultra Alpha-GPC

• Supports memory and learning by supplying the building block for acetylcholine
• Supports focus and mental clarity for work, study and everyday life
• Supports muscle strength as you age by supporting the nerve-to-muscle signals that acetylcholine drives
• Crosses the blood-brain barrier to deliver choline directly to the brain
• Pure and simple: 250 mg of Alpha-GPC per capsule, with no proprietary blends
• 90 capsules per bottle

Why Alpha-GPC?

Not all choline is created equal. Choline bitartrate, the form found in many multivitamins, is inexpensive but far less efficient at delivering choline to the brain. Alpha-GPC is a naturally occurring form of choline found in the brain itself. Because it is roughly 40% choline by weight and crosses the blood-brain barrier efficiently, it gives your brain a direct, reliable supply of the raw material it needs to make acetylcholine, so you get a cognitive advantage you'll notice.

The choline dilemma: why your brain needs a steady supply

Choline does two jobs in your brain at once. It is the raw material for acetylcholine, and it is also a key building block of phosphatidylcholine, a major component of the membranes that surround every brain cell. When choline runs low, research suggests the brain may pull choline out of its own cell membranes to keep making acetylcholine, trading long-term structure for short-term function. Alpha-GPC helps resolve this dilemma by supplying choline for both.

What the research shows

Alpha-GPC has been studied for decades by researchers around the world. Key findings include:

• More than a building block: In addition to supporting acetylcholine, laboratory research suggests Alpha-GPC supports the brain's use of other key messengers, including dopamine and GABA, and helps maintain healthy brain cell membranes.
• Healthy brain aging: Muscarinic M1 receptors, which help brain cells respond to acetylcholine, naturally decline with age. Research in aging models suggests Alpha-GPC helps support these receptors and healthy nerve cell connections.
• Compared with other choline sources: Researchers have reported that Alpha-GPC's benefits compare favorably with older choline sources such as plain choline and lecithin.
• Growth hormone response: In a study of young and older adults, Alpha-GPC enhanced the body's natural growth hormone response, and the effect was more pronounced in older participants. It is one reason Alpha-GPC is popular with active adults and athletes.
• Excellent tolerability: In a large clinical study of more than 2,000 people, only about 2% reported any side effects, and those were mild.

Stay strong as you age: the mind-muscle connection

Starting in our 30s, muscle strength and function begin to slowly decline, and a sedentary lifestyle can speed that process up dramatically. Part of the reason isn't the muscle itself, but the signal that tells it to move. Every movement starts with a nerve releasing acetylcholine at the point where it meets the muscle, called the neuromuscular junction. As we age and move less, that nerve-to-muscle signal can weaken, and muscles that aren't activated regularly begin to lose strength and size.

• Supports muscle activation: Alpha-GPC supplies the choline your body uses to make acetylcholine right at the neuromuscular junction, supporting the strong, reliable signals your muscles need to fire.
• Supports strength and power: In placebo-controlled studies of healthy adults, Alpha-GPC supplementation improved measures of peak force and power output.
• Supports healthy aging: By supporting healthy acetylcholine production, Alpha-GPC helps maintain the connection between brain and muscle that everyday strength, balance and mobility depend on.
• Supports getting back in motion: Whether you are returning to exercise after time off or simply want to stay active, Alpha-GPC supports the nerve-to-muscle communication that helps your muscles respond.

Paired with regular activity, Ultra Alpha-GPC helps you harness the power of acetylcholine to support the strength, power and vitality that keep you feeling youthful, in mind and body.

What's inside (per capsule)

• Alpha-GPC (L-alpha glycerylphosphorylcholine), 250 mg: a highly bioavailable choline source that supports acetylcholine production

Other ingredients: vegetable capsule, silicified microcrystalline cellulose, vegetable stearate.

How to use

Take 2 capsules (500 mg of Alpha-GPC) multiple times per day, or as directed by your healthcare practitioner. Each bottle contains 90 capsules.

Quality you can trust

Ultra Alpha-GPC is made in the USA in a GMP-certified, FDA-registered facility and is lab-tested for purity and potency.

Frequently asked questions

What is acetylcholine?
Acetylcholine is a chemical messenger your brain relies on for memory, learning, attention and muscle control. Your body makes it from choline, which is why a quality choline source like Alpha-GPC matters.

How is Ultra Alpha-GPC different from Brain G-Force™?
Ultra Alpha-GPC is pure, single-ingredient choline support at 250 mg per capsule. Brain G-Force combines 125 mg of Alpha-GPC with galantamine, R-lipoic acid and active B vitamins in a complete memory formula.

How is Alpha-GPC different from citicoline (CDP-choline)?
Both are well-researched choline sources. Alpha-GPC delivers more choline by weight (about 40%) and, in one comparative study, was rated higher for both effectiveness and tolerability.

Who is Ultra Alpha-GPC for?
It is a great fit for anyone who wants to support memory, focus and learning, from students and busy professionals to adults who want to stay strong, active and sharp as they age.

Can I take it with my morning coffee?
Yes. Many people enjoy Ultra Alpha-GPC with a cup of Brain Bean™ Coffee to start the day focused.

Scientific references

1. Life Extension Magazine. GPC: the choline source for brain and body (September 2002). www.lifeextension.com/magazine/2002/9/cover_gpc
2. Traini E, Bramanti V, Amenta F. Choline Alphoscerate (Alpha-Glyceryl-Phosphoryl-Choline) An Old Choline- containing Phospholipid with a Still Interesting Profile As Cognition Enhancing Agent. Current Alzheimer Research. 2013;10(10):1070-1079. doi.org/10.2174/15672050113106660173
3. Ceda G, Ceresini G, Denti L, et al. Alpha-Glycerylphosphorylcholine Administration Increases the GH Responses to GHRH of Young and Elderly Subjects. Hormone and Metabolic Research. 1992;24(03):119-121. doi.org/10.1055/s-2007-1003272
4. Sangiorgi GB, Barbagallo M, Giordano M, et al. α‐Glycerophosphocholine in the Mental Recovery of Cerebral Ischemic Attacks. Annals of the New York Academy of Sciences. 1994;717(1):253-269. doi.org/10.1111/j.1749-6632.1994.tb12095.x
5. Perri RD, Coppola G, Ambrosio LA, et al. A Multicentre Trial to Evaluate the Efficacy and Tolerability of α-Glycerylphosphorylcholine versus Cytosine Diphosphocholine in Patients with Vascular Dementia. Journal of International Medical Research. 1991;19(4):330-341. doi.org/10.1177/030006059101900406
6. Bellar D, LeBlanc NR, Campbell B. The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength. Journal of the International Society of Sports Nutrition. 2015;12(1):42. doi.org/10.1186/s12970-015-0103-x
7. Hasselmo ME. The role of acetylcholine in learning and memory. Current Opinion in Neurobiology. 2006;16(6):710-715. doi.org/10.1016/j.conb.2006.09.002

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.